microscopy imaging

Whole-Slide Imaging

Application Challenges

Whole-slide imaging (WSI) digitizes biological tissue sections at high resolution, enabling precise analysis of tissue structures and cellular morphology. Modern high-throughput scanning can cover entire slide areas in a single experiment, capturing multiscale information from nuclei to tissue-level structures. WSI plays a pivotal role in pathology diagnostics, drug development, and large-scale histological studies.

Because tissue sections are large, structurally complex, and often involve multiple staining or fluorescence labels, high-throughput scanning systems impose demanding requirements on imaging devices: Large FOV format, high resolution, high-speed acquisition, and accurate color reproduction. Furthermore, quantitative precision must be ensured to meet the rigorous standards of professional pathology analysis.

1-1 Brightfield Microscopy
3412

Libra 3412 Series

Global Shutter Monochrome / Color CMOS Cameras

Spectral Response: 350 nm–1100 nm, with enhanced near-infrared response, suitable for multi-channel fluorescence imaging.

Resolution & Pixel Size: 12 MP, 3.4 µm pixels, matching optical sampling requirements below 40× magnification for high detail fidelity.

Color Features: Color models provide AI-based color correction, delivering accurate color reproduction for applications like pathology.

Interface & Speed: Color GigE high-speed interface, full-resolution frame rate up to 98 fps at 12 MP (twice the speed of USB3.0).

Cooling: Mild cooling reduces thermal interference during prolonged operation.

Compact Design: Facilitates system integration and overall performance enhancement.

3243EN

Leo 3243 Pro

Leo 3243 Pro
Large Format High-Throughput sCMOS Camera

Sensor Technology: Stacked BSI sCMOS, achieving a systematic breakthrough in sensitivity, resolution, and speed for high-throughput performance.

Interface: 100G CoF technology, single-interface bandwidth up to 100 Gbps, high-speed and stable, easy to integrate.

Speed & Throughput: 100 fps @ 43 MP, delivering 10× higher data throughput compared to conventional sCMOS cameras.

Large Sensor: 31 mm sensor, single-frame imaging field 2.5× larger than traditional 6.5 µm sCMOS sensors.

Pixel Size: 3.2 µm, optimized for high-precision sampling with optical systems below 40× magnification.

Leo 5514 Pro 2508x1960

Leo 5514 Pro

Large Format High-Throughput BSI sCMOS Camera

Global shutter + BSI sCMOS architecture provides excellent quantitative imaging performance for high-speed weak-light applications
100 G CoF high-speed interface, single interface bandwidth up to 100 Gbps, high-speed and stable, easy to integrate
670 fps @ 14 MP, data throughput increased by 22 times compared to traditional BSI sCMOS cameras
30.5 mm Large FOV, single-frame imaging field of view 2.5 times that of typical 6.5 µm sCMOS
5.5 µm pixel size, better matching the sensitivity and resolution sampling balance for optical systems above 40×

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